Mixed state mania patients display different characteristics
May 5, 2015, BARCELONA, Spain—People who have depressive symptoms during a manic episode appear to have greater psychosocial dysfunction than people with mania but no depressive symptoms, a new study suggests.
When symptoms from the opposite pole occur during mania or depression, that’s referred to as a mood episode with mixed features. Spanish and Chilean researchers looked at 169 adults treated for mania and found 27 per cent experienced mixed features.
The researchers followed the patients for six months and found the mixed-feature group had a greater number of mood episodes overall, more suicidal thinking, more rapid cycling, and more personality disorders. The mixed group also showed a significant trend towards higher psychological dysfunction.
The researchers said their findings highlight the need for better assessment of depressive symptoms in mania to guide treatment.
The study, which appeared in the Australian & New Zealand Journal of Psychiatry, was entitled “Making sense of DSM-5 mania with depressive features.”